Ethnically disparate disease progression and outcomes among acute rheumatic fever patients in New Zealand, 1989-2015

J Oliver; O Robertson; J Zhang; BL Marsters; D Sika-Paotonu; S Jack; J Bennett; DA Williamson; N Wilson; N Pierse; MG Baker

Journal article

Ethnically disparate disease progression and outcomes among acute rheumatic fever patients in New Zealand, 1989-2015

J Oliver, O Robertson, J Zhang, BL Marsters, D Sika-Paotonu, S Jack, J Bennett, DA Williamson, N Wilson, N Pierse, MG Baker

Emerging Infectious Diseases | CENTERS DISEASE CONTROL & PREVENTION | Published : 2021

DOI: 10.3201/eid2707.203045

Open access

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Abstract

We investigated outcomes for patients born after 1983 and hospitalized with initial acute rheumatic fever (ARF) in New Zealand during 1989-2012. We linked ARF progression outcome data (recurrent hospitalization for ARF, hospitalization for rheumatic heart disease [RHD], and death from circulatory causes) for 1989-2015. Retrospective analysis identified initial RHD patients <40 years of age who were hospitalized during 2010-2015 and previously hospitalized for ARF. Most (86.4%) of the 2,182 initial ARF patients did not experience disease progression by the end of 2015. Progression probability after 26.8 years of theoretical follow-up was 24.0%; probability of death, 1.0%. Progression was more..

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University of Melbourne Researchers

Jane Oliver Author

Deborah Williamson Author

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Grants

Awarded by Health Research Council of New Zealand

Funding Acknowledgements

This work was supported by a grant from the New Zealand Lotteries Health Commission, in the form of a PhD scholarship awarded to J.O. and a Health Research Council of New Zealand project grant providing support for M.G.B. and J.B. B.M. was supported by a Pacific Health Research Summer Studentship from the Health Research Council of New Zealand. D.A.W. is supported by a Fellowship from the National Health and Medical Research Council of Australia (GNT 1123854).